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Product Details:
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| Color: | White/Pale Yellow | Packaging: | Foil Bag |
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| CAS: | 50-02-2 | Product Purity: | 99% |
| Product Level:: | Pharmaceutical Grade | Molecular Formula: | C22H29FO5 |
| High Light: | 50-02-2 API Active Pharmaceutical Ingredient,50-02-2 Dexamethasone Powder,Dexamethasone Powder Bodybuilding |
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C22H29FO5 Active Pharmaceutical Ingredient API 50-02-2 Dexamethasone Bodybuilding.
Quick Detail:
Synonyms: 16alpha)-;16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-(11bet;16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-2,20-dione;16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2;16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione;16-alpha-methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-dien;16alpha-Methyl-9alpha-fluoro-11beta-17alpha-21-trihydroxypregna-1,4-diene-3,20-dione;16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol
CAS: 50-02-2
MF: C22H29FO5
MW: 392.46
EINECS: 200-003-9
Chemical Properties White Crystalline Solid
Boiling Point: 568.2 °C at 760 mmHg
Vapour Pressure: 2.81E-15 mmHg at 25 °C
Melting point: 262-264 °C
Storage tempreture: 2-8 °C
Density: 1.32 g/cm3
Solubility: Ethanol: 1 mg/mL
Flash Point: 297.5 °C
Appearance: White crystalline solid
Application:
1). A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase. Dexamethasones is a glucocorticoid used as an anti-inflammatory agent. Dexamethasones regulates T cell survival, growth, and differentiation. Dexamethasones inhibits the induction of nitric oxide synthase.
2). It is injected into the heel when treating plantar fasciitis, sometimes in conjunction with triamcinolone acetonide. It is useful to counteract allergic anaphylactic shock , if given in high doses.
3). It is present in certain eye drops - particularly after eye surgery - and as a nasal spray (trade name Dexacort) , and certain ear drops (Sofradex, when combined with an antibiotic and an antifungal) . Dexamethasones intravitreal steroid implants (trade name Ozurdex) have been approved by the FDA to treat ocular conditions such as diabetic macular edema , central retinal vein occlusion, and uveitis.
4). Dexamethasones is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium . The steroid is released into the myocardium as soon as the screw is extended and can play a significant role in minimizing the acute pacing threshold due to the reduction of inflammatory response . The typical quantity present in a lead tip is less than 1.0 mg.
5). Dexamethasones is often administered before antibiotics in cases of bacterial meningitis . It then acts to reduce the inflammatory response of the body to the bacteria killed by the antibiotics (bacterial death releases proinflammatory mediators that can cause a response which is harmful to the patient), thus improving prognosis and outcome.
COA:
| Product name | Dexamethasones | |
| Appearance | White crystalline powder | |
| Specific optical rotation | Between+72°and +80° | +76.4° |
| Chromatographic purity | Any individual impurity not more than 1.0% Total impurities not more than 2.0% |
0.46% 1.13% |
| Loss on drying | Not more than 0.5% | 0.11% |
| Residue on ignition | Not more than 0.2% | 0.06% |
| Residual solvents | Methanol≤3000ppm Methylene Chloride≤600ppm |
364ppm Not detect out Not detect out Not detect out |
| Assay | Between 97.0% and 102.0% | 98.1% |
| Micronixation | 90% not more than 10 microns | 90% not more than 10 aicrons |
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