CAS 378-44-9 API Active Pharmaceutical Ingredient Anti Inflammatory Betamethasone For Acne

Pharmaceutical Grade Anti Inflammatory Steroids Betamethasone For Acne CAS 378-44-9

Product Name : Betamethasone

CAS No: 378-44-9

Molecular formula : C₂₂H₂₉FO₅

Molecular weight : 392.4611

Natural/synthetic : synthetic

Level : Pharmaceutical grade

Content : 99%

Appearance :White crystalline powder

Application : Mainly used for anti-inflammation and anti-allergy

Packaging : 1KG/Audio Separable

Betamethasone is a steroid medication.It is used for a number of diseases including rheumatic disorders such asrheumatoid arthritisand systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby's lungs, Crohn's disease, cancers such as leukemia, and along with fludrocortisonefor adrenocortical insufficiency, among others. It can be taken by mouth,injected into a muscle, or applied as a cream.When given by injection, anti-inflammatory effects begin in around two hours and last for seven days.

Serious side effects include an increased risk of infection, muscle weakness, severe allergic reactions, and psychosis. Long-term use may cause adrenal insufficiency. Stopping the medication suddenly following long-term use may be dangerous.The cream commonly results in increased hair growth and skin irritation. Betamethasone belongs to theglucocorticoid class of medication.

Betamethasone was patented in 1958 and approved for medical use in the United States in 1961.The cream is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. In the United States the pills and injectable solution are expensive while the cream is not.

Medical uses

Betamethasone is a corticosteroid that is available as pill, by injection, and as a cream.

It is used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate and salicylic acid, or as the combination calcipotriol/betamethasone dipropionate. Betamethasone sodium phosphate is used orally and via injection with the same indications as other steroids. Many betamethasone-based pharmaceuticals include the steroid as the valerate ester.

In a randomized controlled trial betamethasone was shown to reduce some of the ataxia symptoms associated with ataxia telangiectasia(A-T) by 28-31%.

Betamethasone is also used to stimulate fetal lung maturation (to prevent IRDS), and to decrease the incidence and mortality from intracranial hemorrhage in premature infants.

A cream with 0.05% betamethasone appears effective in treating phimosis in boys,and often averts the need forcircumcision.It has replaced circumcision as the preferred treatment method for some physicians in the BritishNational Health Service.

Function:
(1)Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.Unlike other drugs with these effects, betamethasone does not cause water retention.
(2)It is applied as a topical cream, ointment, foam, lotion or gel to treat itching.
(3)Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection (I.M) for itching from various ailments including allergic reactions to poison ivy and similar plants.

A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia.
Hormone class medicine. Mainly used for anti-inflammatory and anti-allergy. Apply to rheumatoid arthritis and various skin diseases. The role of betamethasone with dexamethasone, the anti-inflammatory activity than dexamethasone, triamcinolone, hydrocortisone strong, less side effects.

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