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Product Details:
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| Color: | White/Pale Yellow | Packaging: | Foil Bag |
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| Purity: | 99% | Boiling Point: | 288.125°C At 760 MmHg |
| Flash Point: | 128.054°C | Quality Standard: | USP |
| High Light: | Acetamidophenol Lorcaserin Hcl Powder,Lorcaserin Hcl Powder CAS 846589-98-8,CAS 846589-98-8 Weight Losing Raw Materials |
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Acetamidophenol C8H9NO2 Paracetamol Weight Losing Raw Materials CAS 846589-98-8
Description of Lorcaserin:
| 1 | Lorcaserin is used long term for weight loss in those who are obese. |
| 2 | Lorcaserin is a prescription medication used to help adults who are obese or who are overweight and have weight-related medical problems to lose weight and keep from gaining back that weight. Lorcaserin must be used along with a reduced calorie diet and an exercise plan. |
| 3 | Lorcaserin, currently marketed under the trade name Belviq and previously Lorqess during development, is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic. |
| 4 | Lorcaserin is a selective 5-HT2C receptor agonist, and in vitro testing of the drug showed reasonable selectivity for 5-HT2C over other related targets.5-HT2C receptors are located almost exclusively in the brain, and can be found in the choroid plexus, cortex, hippocampus, cerebellum, amygdala, thalamus, and hypothalamus. The activation of 5-HT2C receptors in the hypothalamus is supposed to activateproopiomelanocortin (POMC) production and consequently promote weight loss through satiety.This hypothesis is supported by clinical trials and other studies. |
Dosage of Lorcaserin:
Lorcaserin is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in obese adults (a BMI of 30 kg/m2 or greater) or in overweight patients (BMI of 27 kg/m2 or greater) with at least one weight-related comorbid condition, such as hypertension, type-2 diabetes, or dyslipidemia.
The recommended dose is 10 mg orally twice daily with or without food. If patients do not achieve a 5% reduction in weight by week 12, they should stop taking lorcaserin because it is unlikely that they will achieve any weight loss with the medication.
Lorcaserin may be used in patients with mild-to-moderate hepatic impairment who require no dose adjustments; however, caution is recommended for patients with severe hepatic impairment, because the effects in this population have not been studied.Although lorcaserin may be used in patients with mild renal impairment, caution is advised for those with moderate renal impairment. The use of lorcaserin in patients with severe renal impairment or end-stage renal failure is not recommended.
Lorcaserin is contraindicated in pregnant women, and it is listed as a Pregnancy Category X medication. It was found to offer no known benefit in pregnant women, because it promotes weight loss.There are no data supporting the use of the medication in nursing mothers.
Fever
Paracetamol is approved for reducing fever in people of all ages. The World Health Organization (WHO) recommends that paracetamol be used to treat fever in children only if their temperature is greater than 38.5 ° C (101.3 ° F). The efficacy of paracetamol by itself in children with fevers has been questioned and a meta-analysis showed that it is less effective than ibuprofen.
Pain
Paracetamol is used for the relief of pains associated with many parts of the body. It has analgesic properties comparable to those of aspirin, while its anti-inflammatory effects are weaker. It is better tolerated than aspirin in patients in whom excessive gastric acid secretion or prolongation of bleeding time may be a concern. Available without a prescription since 1959, it has since become a common household drug.
Paracetamol has relatively little anti-inflammatory activity, unlike other common analgesics such as the NSAIDs aspirin and ibuprofen, but ibuprofen and paracetamol have similar effects in the treatment of headache. Paracetamol can relieve pain in mild arthritis, but has no effect on the underlying inflammation, redness, and swelling of the joint.
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