Orlipastat Weight Losing Raw Materials 96829-58-2 Tetrahydrolipstatin Powder

Orlistat / Tetrahydrolipstatin / Orlipastat Weight Loss Medicine Steroid Powder 96829-58-2

Specification

Description:

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Orlistat blocks some of the fat that you eat, keeping it from being absorbed by your body. Orlistat is used together with a reduced-calorie diet and weight maintenance to treat obesity in people with certain risk factors (such as diabetes, high blood pressure, and high cholesterol or triglycerides).

Orlistat also modestly reduces blood pressure, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

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Applications

A. Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity, is internationally recognized as a new type of lipid-lowering drugs to lose weight.

B. It primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet

C. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.

D. Due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug

Use

1. Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. After orlistat was stopped, a significant number of subjects regained weight- Up to 35% of the weight they had lost.

2. The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%). Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).

Function

It can be used as pharmaceutical material, is often used as an antiestrogenic treatment and may be used by those who have had a poor reaction to testosteron treatments.

The drug has shown to be beneficial in treating sexual dysfunction, impotency and low libido.