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Product Details:
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| Color: | White Powder | Melting Point: | 133-136 °C(lit.) |
|---|---|---|---|
| Storage Temp: | 2-8°C | Water Solubility: | 0.076 G/100 ML |
| BRN: | 1869238 | 4-chloroacetanilide: | Should Comply With Standard |
| High Light: | Pain Relieving Pharmaceutical Intermediates,Pharmaceutical Intermediates 62-44-02,62-44-02 Phenacetin Analgesic Powder |
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Phenacetin Analgesic Powder Pain Relieving Safe Pharmaceutical Intermediates
CAS:62-44-2
MF:C10H13NO2
MW:179.22
EINECS:200-533-0
Synonyms:1-ACETYL-P-PHENETIDIN;4-ACETOPHENETIDIDE;4-acetophenetidine;4'-ETHOXYACETANILIDE;4-ETHOXYACETANILIDE;ACETOPHENETIDIN;ACETOPHENETIDINE;ACET-P-PHENETIDINE
Melting point:133-136 °C(lit.)
Boiling point:132 °C / 4mmHg
Flash point:2℃
storage temp. 2-8°C
form powder
color White
Water Solubility 0.076 g/100 mL
Sensitive Hygroscopic
Merck 14,7204
BRN 1869238
Stability:Stable. Incompatible with strong oxidizing agents, strong acids.
InChIKeyCPJSUEIXXCENMM-UHFFFAOYSA-N
Symbol(GHS)
Abstract
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor make phenacetins-Acetate not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The mild phenacetins-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
Application
Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetis has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treatrheumatoid arthritis (subacute type) and intercostal neuralgia.
Specification
| Test Items | Specification | Test Results |
| Description | Should comply with the standard | Pass |
| Identification | Should be positive reaction | Pass |
| Brownish red 4# | Pass | |
| 4-chloroacetanilide | Should comply with standard | Pass |
| Sulphated ash | ≤0.1% | 0.06% |
| Melting point | 134ºC to 137ºC | 134ºC to 137ºC |
| Appearance | ≥99% | 100.58% |
| Conclusion | Complies with BP68 edition | |
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