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CAS106650-56-0 Sibutramine Slimming material Exporting country

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CAS106650-56-0 Sibutramine Slimming material Exporting country

CAS106650-56-0 Sibutramine  Slimming material Exporting country
CAS106650-56-0 Sibutramine  Slimming material Exporting country CAS106650-56-0 Sibutramine  Slimming material Exporting country CAS106650-56-0 Sibutramine  Slimming material Exporting country

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Product Details:
Place of Origin: India
Brand Name: YUECUI
Certification: ISO9001
Model Number: Pharmaceutical grade
Payment & Shipping Terms:
Minimum Order Quantity: 1KG-1000KG
Price: dollar 1KG $990 per kilogram $950 a kilo for more than 50 kilos
Packaging Details: 25KG 25 kilos a barrel
Delivery Time: 5-8
Payment Terms: Western Union, T/T, D/P, L/C
Supply Ability: 50000KG

CAS106650-56-0 Sibutramine Slimming material Exporting country

Name: Sibutramine Function: Lose Weight
Exporting Country: Individual Countries Contact Information: WhatsApp+13148049998

Introduction to drugs.




Drug name: Sibutramine hydrochloride,


Chemical name :N-{1-[1-(4-chlorophenyl) cyclobutyl] -3-methylbutyl}-N, N' -dimethylamine monohydrate hydrochloride,


Molecular formula :C17H26ClN? HCl? H2O,


Soluble in methanol melting point :193.0~195.0℃


Burning residue :≤0.1%


Heavy metal (Pb):≤10.0ppm


Thin plate chromatography (TLC): Only a single spot


Impurity :≤0.2%


Total impurity :≤0.4% Content :≥99.0%.


Drug nicknames: Trimei, Olina, Nometine Aolina, Reductil


Sibutramine hydrochloride,


Drug description: 10mg: capsule, the content is white or white powder. Tablet :10mg/ tablet.


Usage and dosage: Body mass index (BMI) calculation: weight (kg) divided by height (meters) square value (kg/m2). The recommended starting dose is 10mg once a day, taken in the morning alone or with food. If weight loss is insufficient, the dose can be adjusted to 15mg daily after 4 weeks. If the patient cannot tolerate 10mg dose, it can be reduced to 5mg. The dosage should be adjusted according to the patient's blood pressure and heart rate. Doses above 15mg/ day are not recommended.


Fold edit this paragraph drug action.



Fold sibutramine



Because of the low price of sibutramine, fenfluramine and other drugs, and do have a certain effect of food inhibition and weight loss, has been clever by some illegal businesses to add weight loss food profiteering. Sibutramine has been banned in many countries after it was linked to dozens of deaths in Germany, the United States and Italy. Experts warn that consumers who unknowingly take health food containing this ingredient can have serious consequences. (Some users also appeared some side effects, Sibuqu name will make endocrine disorders, have strong side effects on the skin, such as "fire" symptoms! Attention, please!)


SCOUT study(Sibutramine Cardiovascular Outcome Trial)


From December 2002, a large-scale Trial called SCOUT(Sibutramine Cardiovascular Outcome Trial) was initiated. A total of 9,800 obese and overweight patients took part in the study. The participants were all over 55 years old and had a history of heart disease and diabetes, but had not recently relapsed. The whole experiment lasted six years.


Sibutramine lost an average of only 2kg to 4kg more in the SCOUT group than in a placebo group. And it's not clear that the effect lasts after the drug is stopped. Sibutramine carries a serious but not fatal risk of cardiovascular disease, such as stroke and heart attack. The study led directly to the ban of Sibutramine in the European Union


Folding drug response



Because of the low price, the illegal traders added into the weight loss health products, 98% of the weight loss products on the market are added to the banned ingredients, if you take the reaction in line with most of them, then eat something may be added to the banned ingredients (note: 2,3,5,7, may be added sibutramine hydrochloride):


1. Medications that lose more than 5 kilograms in a week -- taken alone, excluding exercise, dieting and other weight loss measures;


2. Dry mouth


3. Frequent urination


4. Tachycardia


5. Persistent high body temperature


6. Frequent insomnia


7. Bad breath


8. Constipation


9. Headache or dizziness


10. Trance


. Fold and edit this paragraph.




Contraindicated in patients receiving monoamine oxidase inhibitors (MAOI). Contraindicated for patients allergic to the ingredients.


Contraindicated in patients with anorexia nervosa.


Contraindicated in patients receiving other central appetite suppressants.


The treatment of fat gum disease should be based on diet control and exercise.


Organic obesity (such as untreated hypothyroidism) should be excluded from the use of this product.


Blood pressure and pulse should be checked before treatment with this product, and should be monitored regularly during treatment.


Those whose blood pressure and pulse continue to increase while using this drug should consider tapering or discontinuing the drug.


It should be used with caution in patients with a history of hypertension, and should not be used in patients with hypertension whose blood pressure cannot be controlled or controlled poorly.


This product may cause increased heart rate and/or blood pressure. Therefore, certain central diet drugs that cause nerve endings to release serotonin have been associated with heart valve insufficiency.


Two studies were conducted abroad regarding the likelihood of valvular heart disease. In one study 210 patients (mean age 54 years) were observed using 2 and color Doppler echocardiography. These patients had no history of valvular heart disease and had received 15mg sibutramine hydrochloride daily or placebo for a period of 2 weeks to 16 months. Results The incidence of cardiac valvular disease was 3/132(2.3%) in the Sibutramine hydrochloride group and 2/77(2.6%) in the placebo group, with one case of mild aortic insufficiency and one case of severe aortic insufficiency.


In another study using 2 and color Doppler echocardiography, 25 patients were treated with 5 to 30mg of sibutramine hydrochloride daily for 3 months and no valvular disease was observed.


Certain central diet drugs that cause nerve endings to release serotonin can trigger pulmonary hypertension (PPH), a rare but potentially fatal condition.


No similar cases were found in the clinical studies before the product was launched, but it is not certain whether this product will cause this disease because of the low incidence of this disease in the population.


Patients with severe hepatic and renal insufficiency should not take this product.


This product should be used with caution in patients with gallstones because weight loss can increase and aggravate the formation of gallstones.


Because this product can cause pupil dilation, so Qingshen used for angle-closure glaucoma patients.


Use with caution in patients with a history of epilepsy.


Discontinue use in patients with seizures.

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Contact Person: 张国庆

Tel: +861314804998

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